Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

Legionella pneumophila extensively modulates the host ubiquitin network to create the Legionella-containing vacuole (LCV) for its replication.Many of its virulence factors function as ubiquitin ligases or deubiquitinases (DUBs).Here, we identify Lem27 as a DUB that displays a preference for diubiquitin formed by K6, K11, or K48.Lem27 is associated

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